Agammaglobulinaemia Tyrosine Kinase

A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.

Also Known As:

B Cell Progenitor Kinase; Bruton's Tyrosine Kinase; Bruton Tyrosine Kinase; Brutons Tyrosine Kinase; Kinase, Agammaglobulinaemia Tyrosine; Kinase, Bruton's Tyrosine; Tyrosine Kinase, Agammaglobulinaemia; Tyrosine Kinase, Bruton's

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Agammaglobulinaemia Tyrosine Kinase: 1519
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Agammaglobulinaemia Tyrosine Kinase: 1519

Yingying Zuo Selected Research

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Disease

Drug/Important Bio-Agent (IBA)